Evaluation of Interferon-gamma Release Assays, Symptom Screening and Chest Radiograph for Detection of Subclinical Tuberculosis of End-stage Kidney Disease and Kidney Transplant Recipients in Thailand
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
This is an observational study among approximately 160 end-stage renal disease patients on renal replacement therapy and post-living donor or deceased donor kidney transplant recipients. Investigators aim to assess the proportion of positive IGRA associated with symptom development, sputum Xpert MTB/RIF assay, and chest radiograph to define latent TB infection and subclinical TB among ESKD and renal transplant patients.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• End-stage renal disease on renal replacement therapy (hemodialysis or peritoneal dialysis) or status-post-living donor or deceased donor kidney transplantation
• Aged more than or equal 18 years
Locations
Other Locations
Thailand
Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University
RECRUITING
Bangkok
Contact Information
Primary
Tanaya Siripoon, M.D.
Tanaya.sir@mahidol.edu
6626435599
Backup
Punnee Pitisuttithum, Prof. E.
punnee.pit@mahidol.ac.th
6626435599
Time Frame
Start Date: 2024-08-06
Estimated Completion Date: 2027-06-30
Participants
Target number of participants: 160
Treatments
160 End-stage renal disease patients
End-stage renal disease on renal replacement therapy (hemodialysis or peritoneal dialysis) or status-post-living donor or deceased donor kidney transplantation aged more than or equal 18 years
Related Therapeutic Areas
Sponsors
Collaborators: National Research Council of Thailand
Leads: Mahidol University